Exploiting the Power of Stereochemistry in Drugs: An Overview of Racemic and Enantiopure Drugs

@inproceedings{Sekhon2013ExploitingTP,
  title={Exploiting the Power of Stereochemistry in Drugs: An Overview of Racemic and Enantiopure Drugs},
  author={Bhupinder Singh Sekhon},
  year={2013}
}
Abstract: Stereochemistry is one of the essential dimensions in pharmacology as it dictates how enantiomers interact with biological systems. Chirality is very important in drug design. Enantiomers of the same chiral drug can have different pharmacodynamic and/or pharmacokinetic properties. In this context, replacing some existing racemates with single isomers has resulted in improved safety and/or efficacy profile of various racemates. Single enantiomer drug use can potentially lead to simpler… Expand
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