Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions

Abstract

Understanding how individual genes contribute towards the fitness of an organism is a fundamental problem in biology. Although recent genome-wide screens have generated abundant data on quantitative fitness for single gene knockouts, very few studies have systematically integrated other types of biological information to understand how and why deletion of… (More)
DOI: 10.1186/1752-0509-3-74

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Cite this paper

@article{Pache2008ExploitingGD, title={Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions}, author={Roland A. Pache and M. Madan Babu and Patrick Aloy}, journal={BMC Systems Biology}, year={2008}, volume={3}, pages={74 - 74} }