Exploiting Broad-Spectrum Disease Resistance in Crops: From Molecular Dissection to Breeding.

  title={Exploiting Broad-Spectrum Disease Resistance in Crops: From Molecular Dissection to Breeding.},
  author={Wei Li and Yiwen Deng and Yuese Ning and Zuhua He and Guo‐Liang Wang},
  journal={Annual review of plant biology},
Plant diseases reduce crop yields and threaten global food security, making the selection of disease-resistant cultivars a major goal of crop breeding. Broad-spectrum resistance (BSR) is a desirable trait because it confers resistance against more than one pathogen species or against the majority of races or strains of the same pathogen. Many BSR genes have been cloned in plants and have been found to encode pattern recognition receptors, nucleotide-binding and leucine-rich repeat receptors… 

Recent Progress in Rice Broad-Spectrum Disease Resistance

In this review, the most recent advances in the identification of broad-spectrum disease resistance genes in rice and their application in crop improvement through biotechnology approaches during the past 10 years are summarized.

Engineering broad-spectrum disease-resistant rice by editing multiple susceptibility genes.

The results demonstrate that the simultaneous editing of multiple S genes is a powerful strategy for generating new rice varieties with broad-spectrum resistance.

Genomic Approaches to Identify Molecular Bases of Crop Resistance to Diseases and to Develop Future Breeding Strategies

Different approaches, from markers to recent genomic and ‘post-genomic era’ technologies, will be reviewed in order to contribute to a better understanding of the complexity of host–pathogen interactions and genes, including those with small phenotypic effects and mechanisms that underlie resistance.

Susceptibility Is New Resistance: Wheat Susceptibility Genes and Exploitation in Resistance Breeding

Adapted pathogens and pests seriously threaten global wheat production. During pathogen and pest infections, wheat susceptibility (S) genes are exploited to support the compatibility of wheat with

Genome editing for resistance against plant pests and pathogens.

How other technologies, such as host-induced gene silencing (HIGS) and the use of BCAs could benefit from CRISPR/Cas to accelerate the development of green strategies to promote a sustainable agriculture in the future are discussed.

Loss of function of a DMR6 ortholog in tomato confers broad-spectrum disease resistance

A model-to-crop translational work in which two orthologs of the Arabidopsis S gene DMR6 in tomato are characterized, demonstrating that disease resistance correlates with increased salicylic acid levels and transcriptional activation of immune responses and corroborates a mechanism underlying SA homeostasis in plants.

From plant immunity to crop disease resistance.

Development of Rice Variety With Durable and Broad-Spectrum Resistance to Blast Disease Through Marker-Assisted Introduction of Pigm Gene

Rice blast, caused by Magnaporthe oryzae (M. oryzae), is one of the most destructive diseases threatening rice production worldwide. Development of resistant cultivars using broad-spectrum resistance