Exploitation of host signaling pathways by microbial quorum sensing signals.

  title={Exploitation of host signaling pathways by microbial quorum sensing signals.},
  author={Kendra P. Rumbaugh and Gunnar F. Kaufmann},
  journal={Current opinion in microbiology},
  volume={15 2},
Environmental and commensal microbes that live within, on and around us have an enormous impact on human health. Recent progress in studies of prokaryotic interplay as well as host-bacteria interactions suggests that secreted microbial products, including quorum sensing signals (QSS), are important mediators of these intrakingdom and interkingdom relations. Reports have assigned QSS diverse and sometimes seemingly contradictory effects on mammalian cell physiology ranging from either blunting… CONTINUE READING
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