Exploitation of host cells by enteropathogenic Escherichia coli.

  title={Exploitation of host cells by enteropathogenic Escherichia coli.},
  author={Bruce A Vallance and Brett B. Finlay},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={97 16},
Microbial pathogens have evolved many ingenious ways to infect their hosts and cause disease, including the subversion and exploitation of target host cells. One such subversive microbe is enteropathogenic Escherichia coli (EPEC). A major cause of infantile diarrhea in developing countries, EPEC poses a significant health threat to children worldwide. Central to EPEC-mediated disease is its colonization of the intestinal epithelium. After initial adherence, EPEC causes the localized effacement… CONTINUE READING
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