Explicit inclusion of treatment in prognostic modeling was recommended in observational and randomized settings.

Abstract

OBJECTIVES To compare different methods to handle treatment when developing a prognostic model that aims to produce accurate probabilities of the outcome of individuals if left untreated. STUDY DESIGN AND SETTING Simulations were performed based on two normally distributed predictors, a binary outcome, and a binary treatment, mimicking a randomized trial… (More)
DOI: 10.1016/j.jclinepi.2016.03.017

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