Explicit Treatment of Non‐Michaelis‐Menten and Atypical Kinetics in Early Drug Discovery **

@article{Srinivasan2020ExplicitTO,
  title={Explicit Treatment of Non‐Michaelis‐Menten and Atypical Kinetics in Early Drug Discovery **},
  author={Bharath Srinivasan},
  journal={ChemMedChem},
  year={2020},
  volume={16}
}
Biological systems are highly regulated. They are also highly resistant to sudden perturbations enabling them to maintain the dynamic equilibrium essential to sustain life. This robustness is conferred by regulatory mechanisms that influence the activity of enzymes/proteins within their cellular context to adapt to changing environmental conditions. However, the initial rules governing the study of enzyme kinetics were mostly tested and implemented for cytosolic enzyme systems that were easy to… 
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