Explantationstest mit Haut und Peritoneum der neonatalen Ratte als Voraussagetest zur Verträglichkeit lokaler Antiinfektiva für Wunden und Körperhöhlen

  title={Explantationstest mit Haut und Peritoneum der neonatalen Ratte als Voraussagetest zur Vertr{\"a}glichkeit lokaler Antiinfektiva f{\"u}r Wunden und K{\"o}rperh{\"o}hlen},
  author={A. Kramer and V. Adrian and P. Rudolph and S. Wurster and H. Lippert},
  journal={Der Chirurg},
  • A. Kramer, V. Adrian, +2 authors H. Lippert
  • Published 1998
  • Medicine
  • Der Chirurg
  • Summary. In vitro culture of peritoneal explants of neonatal rats after previous application of agents simulating wound antisepsis is a sensitive screening method for the determination of the tissue compatibility of local wound antiinfectives. Two test models are differentiated: (1) separated peritoneal explants as a model for chronic or deep wounds and (2) peritoneum in situ in the experimental animal with subsequent extraction and cultivation of the explants. Considering the present state of… CONTINUE READING
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