Explanation of sterility in txty male mice.

Abstract

The lethal 't alleles' of the T complex on mouse chromosome 17 (refs 1, 2) have been assigned to six complementation groups (the definitive classes being t0, t9, t12, tw1, tw5 and tw73), each causing embryonic death at a particular stage. Intercomplementation heterozygotes (txty) show 'partial' complementation, so that only some txty offspring survive… (More)

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