Expired nitric oxide and airway obstruction in asthma patients with an acute exacerbation.

@article{Crater1999ExpiredNO,
  title={Expired nitric oxide and airway obstruction in asthma patients with an acute exacerbation.},
  author={Scott E Crater and Edward J. Peters and Marie Laure Martin and Andrew W. Murphy and Thomas A. E. Platts-Mills},
  journal={American journal of respiratory and critical care medicine},
  year={1999},
  volume={159 3},
  pages={806-11}
}
Expired nitric oxide (eNO) is a marker of airway inflammation that is increased in asthma. The present study was undertaken to examine the clinical utility of eNO as an aid in the assessment of asthma in the emergency department (ED). Fifty-two adult patients with acute asthma, 53 age- and sex-matched controls, and eight patients with stable asthma were enrolled. Subjects performed spirometry, their eosinophil counts and serum total IgE were measured, and a sample of mixed VC expirate was… CONTINUE READING