Expiratory flow limitation as a determinant of orthopnea in acute left heart failure.

@article{Duguet2000ExpiratoryFL,
  title={Expiratory flow limitation as a determinant of orthopnea in acute left heart failure.},
  author={Alexandre Duguet and Claudio Tantucci and Olivier Lozinguez and Richard Isnard and Dani{\`e}l Thomas and Marc Zelter and J. P. Derenne and Joseph Milic-Emili and Thomas Similowski},
  journal={Journal of the American College of Cardiology},
  year={2000},
  volume={35 3},
  pages={690-700}
}
OBJECTIVES To assess the contribution of expiratory flow limitation (FL) in orthopnea during acute left heart failure (LHF). BACKGROUND Orthopnea is typical of acute LHF, but its mechanisms are not completely understood. In other settings, such as chronic obstructive pulmonary disease, dyspnea correlates best with expiratory FL and can, therefore, be interpreted as, in part, the result of a hyperinflation-related increased load to the inspiratory muscles. As airway obstruction is common in… CONTINUE READING
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