Expert opinion on available options treating pulmonary arterial hypertension.

  title={Expert opinion on available options treating pulmonary arterial hypertension.},
  author={Robert Naeije and Sandrine Huez},
  journal={Expert opinion on pharmacotherapy},
  volume={8 14},
Until in the early nineties, pulmonary arterial hypertension (PAH) was a uniformly fatal disease, with a median life expectancy of approximately 2.5 years. Uncontrolled studies showed that a small proportion of patients responded to high-dose calcium channel blockers, retrospective studies supported the use of anticoagulant therapy and heart-lung or lung transplantation remained the only option. In 1996, a 3-month randomised, placebo-controlled trial showed that chronic intravenous epoprostenol… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…