Experiments on the Survival of the Febrile Herpetic and Allied Viruses

  • H. F. strain-comprised
  • Published 2004


Much interest centers at present about the subject of the etiology of epidemic (lethargic) encephalitis and of febrile herpes. In both conditions a virus has been described as the incitant, but the properties of the two viruses are so nearly alike that as yet they cannot be separated by animal tests. There is a general agreement among investigators, however, regarding the qualities of the active agent, or the invisible infecting microorganism of febrile herpes associated with the experimental lesions characterizing the condition. In the case of the so called virus of encephalitis lethargica, on the other hand, different workers have isolated organisms varying widely in their morphological and cultural characteristics, each of which has been regarded as the incitant of the disease. At the request of Dr. Flexner, I undertook to repeat certain experiments on the cultivation of the so called virus of epidemic encephalitis outside the body which were reported by Bradford, Bashford, and Wilson,' by Loewe and Strauss,2 and by Thalhimer.3 These observers claim to have isolated, by means of the Smith-Noguchi technique, organisms resembling the globoid bodies of poliomyelitis. Although the results were negative and I was unable to confirm the work of the authors named, it seems desirable to report the experiments. Incidentally, the experimental data refute published reports of positive cultures of quite common bacterial species de-

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Cite this paper

@inproceedings{straincomprised2004ExperimentsOT, title={Experiments on the Survival of the Febrile Herpetic and Allied Viruses}, author={H. F. strain-comprised}, year={2004} }