Experiments on the Carcinogenicity and Reactivity of β-propiolactone

@article{Searle1961ExperimentsOT,
  title={Experiments on the Carcinogenicity and Reactivity of $\beta$-propiolactone},
  author={C. E. Searle},
  journal={British Journal of Cancer},
  year={1961},
  volume={15},
  pages={804 - 811}
}
fi-PROPIOLACTONE (3-hydroxypropionic acid lactone, O.CH2.CH2C: O) is a highly reactive compound of simple structure which is now available in quantity. It has many possible uses as an organic synthetic agent, and has been recommended for sterilising plasma (Hartmann, LoGrippo and Kelly, 1954) and arterial grafts (Rains et al., 1956) and as a toxoiding agent in place of formalin (Orlans and Jones, 1958). It is therefore of importance that ,-propiolactone, besides being a vesi-cant, is also a… Expand
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