Experiments on the Action of Emetine in Cultures of Entamoeba Coli.

@article{BishopExperimentsOT,
  title={Experiments on the Action of Emetine in Cultures of Entamoeba Coli.},
  author={Ann Bishop},
  journal={Parasitology},
  volume={21},
  pages={481 - 486}
}
  • A. Bishop
  • Published 1 December 1929
  • Biology
  • Parasitology
1. Two pure strains of Entamoeba coli, differing in their accompanying bacterial flora and experimental history, but identical morphologically, have been tested with emetine hydrochloride in vitro. 2. In a buffered and wholly liquid medium, with a pH varying between 6·8 and 7·2, emetine hydrochloride was found to be toxic to E. coli in dilutions between 1 : 300,000 and 1 : 600,000, the toxicity increasing with the alkalinity of the medium. 3. It is therefore concluded that emetine is about 16… 
7 Citations

The action of amoebicidal drugs on Entamoeba invadens Rodhain, 1934 in vitro

The sensitivity of di- and monobacterial strains of E. invadens to emetine was determined, and of a dibacterial strain to the quinaldines A 352, A 356 and A 404, and a strain which was maintained for 9 months in the presence of increasing concentrations ofEmetine did not become resistant to the drug.

Researches on the intestinal Protozoa of monkeys and man

It is demonstrated conclusively that, although the aerobic bacteria individually induced the cysts of E. histolytica to hatch and supported the growth of the amoebae indefinitely, only one species—the anaerobe N5—was capable of promoting encystation.

Researches on the Intestinal Protozoa of Monkeys and Man

It has been found impossible to distinguish various strains of “E. coli” living in macaques, a marmoset, and men, by any recognizable specific feature, and it is concluded that no specific difference actually exists between any of them.

Researches on the Intestinal Protozoa of Monkeys and Man

It is concluded that E. nana naturally lives not only in Man but also in at least 3 different species of Macacus, and probably in monkeys of this genus generally, and there is evidence (from the work of others) that this amoeba may inhabit some other domestic mammals.

Ann Bishop, 19 December 1899 - 7 May 1990

Ann Bishop was an eminent protozoologist and parasitologist who spent almost her entire career in Cambridge where she was a Fellow of Girton College for nearly 60 years. Her main work was concerned

References

SHOWING 1-4 OF 4 REFERENCES

Further Experiments on the Action of Emetine in Cultures of Entamoeba histolytica

In 1926 two of us published the results of a long series of experiments on the toxic action of the alkaloids of ipecacuanha in cultures of several species of entozoic amoebae, which showed clearly that the full specific action of emetine is only disclosed if the alkAloid is allowed to act for a sufficient time.

The Action of Ipecacuanha Alkaloids on Entamoeba histolytica and some other Entozoic Amoebae in Culture

It is now recognized, by all competent observers, that emetine is a specific therapeutic agent for the treatment of amoebic dysentery; but although it is known that a thorough course of emetine, in

On the Cultivation of Entamoeba histolytica and some other Entozoic Amoebae

Methods by which cultures of entozoic amoebae can be initiated from encysted forms have been discovered and are described, and some indications are given for the isolation of pure strains from mixed cultures.

The Effect of Increased and Decreased Oxygen Pressure upon the Intestinal Protozoa of Macacus rhesus

In his experiments upon the toxicity of oxygen for protozoa Cleveland (1925, a, b, c) was able to kill the intestinal protozoa of Termites, without injuring the host, by increasing the pressure of