Experimental validation and computational modeling of anti-influenza effects of quercetin-3-O-α-L-rhamnopyranoside from indigenous south African medicinal plant Rapanea melanophloeos

@article{Mehrbod2019ExperimentalVA,
  title={Experimental validation and computational modeling of anti-influenza effects of quercetin-3-O-α-L-rhamnopyranoside from indigenous south African medicinal plant Rapanea melanophloeos},
  author={P. Mehrbod and S. Ebrahimi and F. Fotouhi and Fatemeh Eskandari and Jacobus N. Eloff and L. McGaw and F. Fasina},
  journal={BMC Complementary and Alternative Medicine},
  year={2019},
  volume={19}
}
  • P. Mehrbod, S. Ebrahimi, +4 authors F. Fasina
  • Published 2019
  • Medicine, Biology
  • BMC Complementary and Alternative Medicine
  • BackgroundInfluenza A virus (IAV) is still a major health threat. The clinical manifestations of this infection are related to immune dysregulation, which causes morbidity and mortality. The usage of traditional medication with immunomodulatory properties against influenza infection has been increased recently. Our previous study showed antiviral activity of quercetin-3-O-α-L-rhamnopyranoside (Q3R) isolated from Rapanea melanophloeos (RM) (L.) Mez (family Myrsinaceae) against H1N1 (A/PR/8/34… CONTINUE READING
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    References

    SHOWING 1-10 OF 82 REFERENCES
    Immunomodulatory properties of quercetin-3-O-α-L-rhamnopyranoside from Rapanea melanophloeos against influenza a virus
    • 14
    Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication.
    • H. J. Choi, J. Song, K. S. Park, D. Kwon
    • Biology, Medicine
    • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
    • 2009
    • 116
    In vitro and in vivo mechanism of immunomodulatory and antiviral activity of Edible Bird's Nest (EBN) against influenza A virus (IAV) infection.
    • 23
    • PDF
    Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection
    • 21
    • PDF
    Antiviral activity of a synthesized shikonin ester against influenza A (H1N1) virus and insights into its mechanism.
    • 12
    Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry
    • 115
    • PDF
    Prophylactic effect of herbal-marine compound (HESA-A) on influenza A virus infectivity
    • 6
    • PDF
    South African medicinal plant extracts active against influenza A virus
    • 20