Experimental urethane anaesthesia prevents digoxin intoxication: electrocardiographic and histological study in rabbit.

@article{Princi2000ExperimentalUA,
  title={Experimental urethane anaesthesia prevents digoxin intoxication: electrocardiographic and histological study in rabbit.},
  author={Tanja Princi and Giorgio Delbello and Vittorio Grill},
  journal={Pharmacological research},
  year={2000},
  volume={42 4},
  pages={
          355-9
        }
}
An electrocardiographic and histological study was performed in rabbit to detect the effects of urethane (ethyl carbamate) intraperitoneal (i.p.) anaesthesia in digoxin intoxication, since it has been previously shown that this anaesthetic and digitalis glycosides exert specific peripheral effects on the cardiovascular system involving central structures of the autonomic nervous system. We observed that i.p. urethane anaesthesia prevented the onset of the electrocardiographic signs of digitalis… CONTINUE READING
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