Experimental ultrasonic angioplasty: disruption of atherosclerotic plaques and thrombi in vitro and arterial recanalization in vivo.

@article{Rosenschein1990ExperimentalUA,
  title={Experimental ultrasonic angioplasty: disruption of atherosclerotic plaques and thrombi in vitro and arterial recanalization in vivo.},
  author={Uri Rosenschein and Jerald J. Bernstein and E Disegni and Elieser Kaplinsky and Jacques Bernheim and L A Rozenzsajn},
  journal={Journal of the American College of Cardiology},
  year={1990},
  volume={15 3},
  pages={711-7}
}
To investigate the use of high energy ultrasound as an alternative energy for angioplasty, an experimental ultrasonic angioplasty device was developed. The device was studied in two bioassay systems: an in vitro system for the disruption of atherosclerotic plaques and thrombi and an in vivo system for the recanalization of occluded canine femoral arteries. In vitro, sonication efficiently reduced the size of the plaques. Atheromatous plaques (n = 11) disrupted at a rate of 21 +/- 8 s/cm2… CONTINUE READING