Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis.

@article{Balam2005ExperimentalTM,
  title={Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis.},
  author={Tarek Abdulsamad Balam and Takashi Yamashiro and Li Zheng and Sakhr Murshid Ahmed and Yoshiaki Fujiyoshi and Teruko Takano-Yamamoto},
  journal={Brain research},
  year={2005},
  volume={1036 1-2},
  pages={196-201}
}
Levels of preproenkephalin mRNA expression in trigeminal subnucleus complex by noxious tooth movement stimuli were examined using in situ hybridization. At 24 h, preproenkephalin mRNA expression was significantly upregulated in the ipsilateral trigeminal subnucleus caudalis (P<0.05), and in the subnucleus oralis (P<0.05). These findings suggested that enkephalinergic inhibitory systems could be activated during tooth movement, and that subnucleus oralis may be involved in modulation of the… CONTINUE READING