Experimental therapy of onchocerciasis with suramin and hetrazan; results of a three-year study.

@article{Burch1951ExperimentalTO,
  title={Experimental therapy of onchocerciasis with suramin and hetrazan; results of a three-year study.},
  author={T. Burch and L. L. Ashburn},
  journal={The American journal of tropical medicine and hygiene},
  year={1951},
  volume={31 5},
  pages={
          617-23
        }
}
  • T. Burch, L. L. Ashburn
  • Published 1951
  • Biology, Medicine
  • The American journal of tropical medicine and hygiene
  • Summary Hetrazan had a spectacular and immediate effect against the microfilariae of Onchocerca volvulus but since it did not destroy the adult worms the disappearance of microfilariae was only temporary. Intravenous suramin, on the other hand, caused a more gradual disappearance of the microfilariae but since it also killed the adult worms, this disappearance was permanent in about 90 per cent of cases. Simultaneous treatment with intravenous suramin and oral Hetrazan combined the rapid action… CONTINUE READING
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