Experimental therapeutic assays of Tephrosia vogelii against Leishmania major infection in murine model: in vitro and in vivo

@article{Marango2017ExperimentalTA,
  title={Experimental therapeutic assays of Tephrosia vogelii against Leishmania major infection in murine model: in vitro and in vivo},
  author={Sylvia Naliaka Marango and Christopher Khayeka–Wandabwa and Judith Alice Makwali and Bernard N. Jumba and Joseph Kiprop Choge and Eric Onyango Adino and Christopher O. Anjili},
  journal={BMC Research Notes},
  year={2017},
  volume={10}
}
BackgroundConventional targeted leishmanicidal chemotherapy has persistently remained prohibitive for most economically deprived communities due to costs, associated time to accessing health services and duration for successful treatment programme. Alternatives are bound to be incorporated in rational management of leishmaniasis by choice or default due to accessibility and cultural beliefs. Therefore, there is need to rigorously investigate and appraise the activity of medicinal compounds that… Expand
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Phytochemical Analysis of Tephrosia vogelii across East Africa Reveals Three Chemotypes that Influence Its Use as a Pesticidal Plant
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Analysis of methanolic extracts of foliar parts of T. vogelii revealed the occurrence of two distinct chemotypes that were separated by the presence of rotenoids in one, and flavanones and flavones that are not bioactive against insects on the other. Expand
Phytochemical Analysis of across East Africa Reveals Three Chemotypes that Influence Its Use as a Pesticidal Plant
Tephrosia vogelii is a plant species chemically characterized by the presence of entomotoxic rotenoids and used widely across Africa as a botanical pesticide. Phytochemical analysis was conducted toExpand

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