Experimental subendocardial ischemia in dogs with normal coronary arteries.

@article{Buckberg1972ExperimentalSI,
  title={Experimental subendocardial ischemia in dogs with normal coronary arteries.},
  author={Gerald D. Buckberg and David E. Fixler and J. P. Archie and Julien I E Hoffman},
  journal={Circulation research},
  year={1972},
  volume={30 1},
  pages={67-81}
}
Subendocardial ischemia without anatomic coronary artery obstruction may result from a discrepancy between metabolic needs and available blood supply. We studied this in open-chest anesthetized dogs and measured pressures in aorta and left ventricle (LV), phasic left coronary arterial blood flow (CBF) by electromagnetic flowmeter, total CBF and LV subendocardial (endo) and subepicardial (epi) flow with radioactive microspheres 8— 10fi in diameter. Since LV subendocardial flow is mainly or… CONTINUE READING
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