Experimental subarachnoid hemorrhage: subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat models.

@article{Prunell2003ExperimentalSH,
  title={Experimental subarachnoid hemorrhage: subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat models.},
  author={Giselle Fabiana Prunell and T. G. Mathiesen and Nils Henrik Diemer and N. -Aa. Svendgaard},
  journal={Neurosurgery},
  year={2003},
  volume={52 1},
  pages={
          165-75; discussion 175-6
        }
}
OBJECTIVE To investigate which of three subarachnoid hemorrhage (SAH) models is the most suitable for studies of pathological and pathophysiological processes after SAH. METHODS SAH was induced in rats via intracranial endovascular perforation (perforation model), blood injection into the cisterna magna (300 microl), or blood injection into the prechiasmatic cistern (200 microl). The subarachnoid blood volume was quantitatively measured. Cerebral blood flow (CBF) (as assessed with laser… CONTINUE READING
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