Experimental study of the detrimental effect of dopamine/glucagon combination in d,l-propranolol intoxication.

@article{Toet1996ExperimentalSO,
  title={Experimental study of the detrimental effect of dopamine/glucagon combination in d,l-propranolol intoxication.},
  author={Alexander Toet and Johan Wemer and Wim Vleeming and J D te Biesebeek and Jan Meulenbelt and Dick J de Wildt},
  journal={Human & experimental toxicology},
  year={1996},
  volume={15 5},
  pages={411-21}
}
1. Respiratory and cardiovascular failure are the principle toxic effects of beta-blocker overdose. Respiratory arrest is the primary cause of death in beta-blocker intoxicated rats. 2. The effect of glucagon, dopamine and the combination of glucagon/dopamine on respiratory and cardiovascular function and survival time in beta-blocker overdose was investigated in a model of acute d,l-propranolol (resp. 30 and 15 mg kg-1 h-1 in rat and rabbit) intoxication in spontaneously breathing rats and… CONTINUE READING

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