Experimental study of extracorporeal perfusion for septic shock.

  title={Experimental study of extracorporeal perfusion for septic shock.},
  author={Takashi Sato and James P. Orlowski and Maciej Zborowski},
  journal={ASAIO journal},
  volume={39 3},
The authors evaluated the efficacy of treatment by extracorporeal perfusion on experimental canine septic shock. Canine septic shock was produced by intravenous infusion of Escherichia coli endotoxin and treated by three techniques: no treatment (Sham), hemoperfusion over Polymyxin B immobilized fiber (PMX), and plasma perfusion over anion exchange resin (Resin). The 24 hr survival rates of the Sham, PMX, and Resin groups were 0%, 80%, and 40%, respectively. In the PMX group, blood pressure was… CONTINUE READING


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