Experimental studies of tumor immunotherapy. I. Macrophage migration inhibitory activity as an immunological parameter.

@article{Hayashi1976ExperimentalSO,
  title={Experimental studies of tumor immunotherapy. I. Macrophage migration inhibitory activity as an immunological parameter.},
  author={Shin-ichi Hayashi},
  journal={Acta medica Okayama},
  year={1976},
  volume={30 2},
  pages={
          95-106
        }
}
The macrophage migration inhibition activity [MI activity) was stable in sensitized lymphocyte-to-marcophage ratios of 1:5 to 1:20 in mice. Antigen protein concentrations under 100 mug/ml did not induce nonspecific macrophage migration inhibition. Inhibition of tumor proliferation and survival was observed after a combined injection of BCG and MH-134 cells. After a single injection of MH-134 tumor cells, MI activity was reinforced and prolonged, demonstrating the clear effects of BCG as… CONTINUE READING

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