Experimental striatal degeneration induced by kainic acid administration: relevance to morphological changes in Huntington's disease.

In an attempt to reproduce the characteristic neuronal degeneration pattern in the striatum of human patients with Huntington's disease, the histological and ultrastructural features of the degeneration of medium-sized nerve cells in the striatum and its processes are described in young rats induced by a direct injection of a small amount of kainic acid… CONTINUE READING