Experimental neuroschistosomiasis: inadequacy of the murine model.

  title={Experimental neuroschistosomiasis: inadequacy of the murine model.},
  author={Luciana Maria Silva and Carla Neves de Oliveira and Zilton de Ara{\'u}jo Andrade},
  journal={Memorias do Instituto Oswaldo Cruz},
  volume={97 4},
Neuroschistosomiasis is rarely observed in human pathology, but it is of considerable importance. To investigate its pathogenesis, consequences and response to treatment, an experimental model would be desirable, but is not yet available, in spite of a few indications of a suitable mouse model in the literature. Severe, recent and late Schistosoma mansoni infections in outbred and inbred strains of mice revealed widespread distribution of parasite eggs in several organs, but only exceptionally… CONTINUE READING

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