Experimental myocardial infarction. Induction of coronary thrombosis in the intact closed-chest dog.

@article{SALAZAR1961ExperimentalMI,
  title={Experimental myocardial infarction. Induction of coronary thrombosis in the intact closed-chest dog.},
  author={AerogelR. SALAZAR},
  journal={Circulation research},
  year={1961},
  volume={9},
  pages={1351-6}
}
THE DIFFICULTY of inducing consistent, reproducible, segmental arterial thrombosis in the experimental animal has been highlighted in recent literature and constitutes one of the stumbling blocks in the study of occlusive arterial disease. As pointed out by J. R. 0 'Brien in his exhaustive review of the subject, "the immediate precipitating stimulus necessary for the formation of a thrombus in an apparently healthy vessel remains completely unknown." Our interest in the phenomena associated… CONTINUE READING
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