Experimental modifications and changes with age in pineal succinic dehydrogenase activity.

@article{Quay1959ExperimentalMA,
  title={Experimental modifications and changes with age in pineal succinic dehydrogenase activity.},
  author={Wilbur B. Quay},
  journal={The American journal of physiology},
  year={1959},
  volume={196 5},
  pages={
          951-5
        }
}
Pineal succinic dehydrogenase was determined by means of reduction of 2,3,5-triphenyl-2H-tetrazolium chloride and colorimetry. Studies employing over 3300 rats, primarily of the Long-Evans strain, demonstrate that: a ) Al+++ and Ca++ promote and Cu++, malonate, iodine and hydroquinone inhibit enzyme activity in vitro; b ) enzyme activity more than doubles in both sexes during the first 6 weeks postnatally with some reduction probable in about 1 year; c ) pineal activity equals 50% of that of… CONTINUE READING