Experimental models of right heart failure: a window for translational research in pulmonary hypertension.

@article{Guihaire2013ExperimentalMO,
  title={Experimental models of right heart failure: a window for translational research in pulmonary hypertension.},
  author={Julien Guihaire and Harm Jan Bogaard and Erwan Flecher and Pierre-Emmanuel Noly and Olaf Mercier and François Haddad and {\'E}lie Fadel},
  journal={Seminars in respiratory and critical care medicine},
  year={2013},
  volume={34 5},
  pages={
          689-99
        }
}
The right ventricle (RV) faces major changes in loading conditions associated with cardiovascular and pulmonary vascular disorders. Despite major pharmacological advances since the last decade, pulmonary arterial hypertension remains a deadly disease mainly secondary to the development of right ventricular failure (RVF). Several experimental models of RVF have been developed over the past three decades providing a particular insight in RV pathophysiology. Mechanisms involved in the transition… CONTINUE READING
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