Experimental models of invasion and metastasis; can they provide reliable answers for the role of proteases in cancer?


This paper discusses the feasibility of extrapolating to human cancer results obtained concerning the role of proteases in experimental models of invasion and metastasis. It is customary to view metastasis as a series of individual steps, which must be completed in sequence for the process to be successful. The role of proteases in this process is usually… (More)