Experimental models of endotoxaemia related to abortion in the mare.

@article{Kindahl1991ExperimentalMO,
  title={Experimental models of endotoxaemia related to abortion in the mare.},
  author={Hans Kindahl and Peter F. Daels and Kristina Odensvik and David Daunt and G Fredricksson and G H Stabenfeldt and J. P. Hughes},
  journal={Journal of reproduction and fertility. Supplement},
  year={1991},
  volume={44},
  pages={509-16}
}
Three different routes of administering Salmonella typhimurium endotoxin to mimic naturally occurring endotoxaemia were tried in the mare. Bolus injection, repeated bolus injections and continuous low-dose infusion were compared with prostaglandin F2 alpha release, leucocyte count and clinical response. A biphasic prostaglandin release and a pronounced leucopenia of almost identical patterns were seen in all models. Repeated bolus injections showed that the second injection initiated only a… CONTINUE READING

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