Experimental models of cerebral malaria.

  title={Experimental models of cerebral malaria.},
  author={Christian R Engwerda and Elodie Belnoue and Anne Charlotte Gr{\"u}ner and Laurent R{\'e}nia},
  journal={Current topics in microbiology and immunology},
Malaria remains a major global health problem and cerebral malaria is one of the most serious complications of this disease. Recent years have seen important advances in our understanding of the pathogenesis of cerebral malaria. Extensive analysis of tissues and blood taken from patients with cerebral malaria has been complimented by the use of animal models to identify specific components of pathogenic pathways. In particular, an important role for CD8+ T cells has been uncovered, as well… CONTINUE READING