Experimental models and behavioural tests used in the study of Parkinson's disease.

@article{Mokr1995ExperimentalMA,
  title={Experimental models and behavioural tests used in the study of Parkinson's disease.},
  author={Jaroslav Mokrỳ},
  journal={Physiological research},
  year={1995},
  volume={44 3},
  pages={143-50}
}
The present review brings the survey of the most frequently used behavioural tests in experimental models of Parkinson's disease (PD). Although there is no spontaneous occurrence of parkinsonism in animals, several experimental animal models of PD have been developed to achieve the same clinical features in animals. The techniques employing neurotoxins in lesioning the nigrostriatal dopaminergic (DA) system have a large selectivity and reproducibility. The most frequently used neurotoxins are 1… CONTINUE READING