Experimental modeling of spinal cord injury: characterization of a force-defined injury device.

@article{Scheff2003ExperimentalMO,
  title={Experimental modeling of spinal cord injury: characterization of a force-defined injury device.},
  author={Stephen William Scheff and Alexander G. Rabchevsky and Isabella Fugaccia and John A. Main and James E. Lumpp},
  journal={Journal of neurotrauma},
  year={2003},
  volume={20 2},
  pages={
          179-93
        }
}
We examined the ability of a novel spinal cord injury (SCI) device to produce graded morphological and behavioral changes in the adult rat following an injury at thoracic level 10 (T10). The injury device uses force applied to the tissue as the control variable rather than tissue displacement. This has the advantage of eliminating errors that may arise from tissue movement prior to injury. Three different injury severities, defined by the amount of force applied to the exposed spinal cord at… CONTINUE READING
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