Experimental meningeal carcinomatosis selectively depresses local cerebral glucose utilization in rat brain.

Abstract

Using quantitative autoradiography, we investigated the effect of meningeal carcinomatosis on local cerebral glucose utilization (LCGU). A rat model of meningeal carcinomatosis using Walker 256 tumor was used. LCGU was evaluated using 14C-2-deoxy-D-glucose according to the Sokoloff method. Thirty-one neuroanatomic structures were evaluated, both separately… (More)

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@article{Hiesiger1989ExperimentalMC, title={Experimental meningeal carcinomatosis selectively depresses local cerebral glucose utilization in rat brain.}, author={Emile M. Hiesiger and A Picco-Del Bo and Lauren E. Lipschutz and G{\'e}rard Basler and Howard T. Thaler and Jessica Posner and William R. Shapiro}, journal={Neurology}, year={1989}, volume={39 1}, pages={90-5} }