Experimental infections with enteroviruses

  title={Experimental infections with enteroviruses},
  author={D. T.Y.LouM. and D. H.A.WennerM.},
  journal={Archiv f{\"u}r die gesamte Virusforschung},
  • T. Y. Lou M. D., H. A. Wenner M. D.
  • Published 2005 in Archiv für die gesamte Virusforschung
  • DOI:10.1007/BF01258133
Young adult cynomolgus monkeys are susceptible to infection from Coxsackie A type 16 virus following parenteral inoculation. After infection monkeys may develop fever and neuromuscular disability associated with extensive injury to neurones of the spinal cord and brain stem. Focal myositis developed in 2 monkeys. Monkeys may develop measurable viremia; Coxsackie A 16 virus was not recovered from CNS or other tissues. Following infection type specific antibodies develop. Cutaneous lesions were… CONTINUE READING