Experimental infection of sheep with visna/maedi virus via the conjunctival space.

@article{Niesalla2008ExperimentalIO,
  title={Experimental infection of sheep with visna/maedi virus via the conjunctival space.},
  author={Heide Niesalla and Tom N. McNeilly and Margaret Ross and Susan M. Rhind and Gordon D. Harkiss},
  journal={The Journal of general virology},
  year={2008},
  volume={89 Pt 6},
  pages={
          1329-37
        }
}
Experiments were performed to determine whether visna/maedi virus (VMV), a small ruminant lentivirus (SRLV), could infect sheep via ocular tissues. The EV1 strain of VMV was administered into the conjunctival space of uninfected sheep, and the animals monitored for the presence of provirus DNA and anti-VMV antibodies in blood. The results showed that provirus DNA appeared in peripheral blood mononuclear cells of all animals within a few weeks of receiving either 10(6) TCID50 or 10(3) TCID50 of… CONTINUE READING

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