Experimental infection of domestic canaries (Serinus canaria domestica) with Mycoplasma gallisepticum: a new model system for a wildlife disease

@article{Hawley2011ExperimentalIO,
  title={Experimental infection of domestic canaries (Serinus canaria domestica) with Mycoplasma gallisepticum: a new model system for a wildlife disease},
  author={Dana M. Hawley and Jessica L Grodio and Salvatore Frasca and Laila T. Kirkpatrick and David H Ley},
  journal={Avian Pathology},
  year={2011},
  volume={40},
  pages={321 - 327}
}
The ethical and logistical challenges inherent in experimental infections of wild-caught animals present a key limitation to the study of wildlife diseases. Here we characterize a potentially useful domestic model for a wildlife disease that has been of particular interest in recent decades; that is, infection of North American house finches (Carpodacus mexicanus) with Mycoplasma gallisepticum, more commonly known as a worldwide poultry pathogen. Seven domestic canaries (Serinus canaria… Expand
Pathogenicity and immunogenicity of three Mycoplasma gallisepticum isolates in house finches (Carpodacus mexicanus).
TLDR
Evidence is provided that MG strains or strain variants circulating in house finch populations vary in their ability to cause disease, induce antibody responses, and persist in the host. Expand
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Attenuated Phenotype of a Recent House Finch-Associated Mycoplasma gallisepticum Isolate in Domestic Poultry
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Virulence in domestic poultry with two temporally distant, and yet geographically consistent, HFMG isolates which differ in virulence for house finches is assessed, indicating that a recent isolate of HFMG is greatly attenuated in the chicken host relative to the index isolate. Expand
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TLDR
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House finches with high coccidia burdens experience more severe experimental Mycoplasma gallisepticum infections
TLDR
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Mycoplasma gallisepticum and Escherichia coli mixed infection model in broiler chickens for studying valnemulin pharmacokinetics.
TLDR
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The influence of host tissue on M. gallisepticum vlhA gene expression.
TLDR
There are significant differences in vlhA gene expression patterns between M. gallisepticum collected from chicken tracheas compared to those collected from house finch conjunctiva, which suggest that discrete suites of vlHA genes may be involved in M.galliseptum pathogenesis and tropism for unique tissues in two disparate avian hosts. Expand
Differential house finch leukocyte profiles during experimental infection with Mycoplasma gallisepticum isolates of varying virulence
TLDR
Significant temporal effects of MG infection on the proportions of most cell types are found, with strong increases in heterophil and monocyte proportions during infection, and variation in infection severity positively predicted the proportion of circulating heterophils and lymphocytes. Expand
Differing House Finch Cytokine Expression Responses to Original and Evolved Isolates of Mycoplasma gallisepticum
TLDR
The extent of pro-inflammatory interleukin 1 beta signaling was correlated with conjunctival MG loads and the extent of clinical signs of conjunctivitis, the main pathological effect of MG in house finches. Expand
Deposition of pathogenic Mycoplasma gallisepticum onto bird feeders: host pathology is more important than temperature-driven increases in food intake
TLDR
The results suggest that in this system, host physiological responses are more important for transmission potential than temperature-dependent alterations in feeding, which is critical to linking individual responses to climate with population-level disease dynamics. Expand
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