Experimental infection of bulls with a genital isolate of bovine herpesvirus-4 and reactivation of latent virus with dexamethasone.

@article{Dubuisson1989ExperimentalIO,
  title={Experimental infection of bulls with a genital isolate of bovine herpesvirus-4 and reactivation of latent virus with dexamethasone.},
  author={Jean Dubuisson and {\'E}tienne Thiry and Michel Bublot and I R Thomas and Marie-Françoise Van Bressem and Freddy L. Coignoul and P. P. Pastoret},
  journal={Veterinary microbiology},
  year={1989},
  volume={21 2},
  pages={97-114}
}
Five 13- to 18-month old Belgian Blue bulls were used in this experiment. Four bulls (Nos. 2, 3, 4 and 5) were inoculated intratesticularly with 10(5) plaque-forming units of bovine herpesvirus-4 (BHV-4) in each testicle (Day 0). The challenge BHV-4 strain was previously isolated from testicle cells of a bull exhibiting orchitis and azoospermia. The fifth bull (No. 1) was used as a control and received the same volume of uninfected cell culture supernatant. For 5 days, beginning on Day 51 post… CONTINUE READING