Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4

@article{Gancz2009ExperimentalIO,
  title={Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4},
  author={Ady Y Gancz and Amy L. Kistler and Alexander L Greninger and Yigal Farnoushi and Sara Mechani and Shmuel Perl and Asaf Berkowitz and Noa Perez and Susan L Clubb and Joseph L. DeRisi and Donald E Ganem and Avishai Lublin},
  journal={Virology Journal},
  year={2009},
  volume={6},
  pages={100 - 100}
}
Proventricular dilatation disease (PDD) is a fatal disorder of psittacine birds worldwide. The disease is characterized by lymphoplasmacytic infiltration of the central and peripheral nervous systems, leading to gastrointestinal motility and/or central nervous system dysfunction. Recently, we detected a significant association between avian bornavirus (ABV) infection and clinical signs of PDD in psittacines. However, it remains unclear whether ABV infection actually causes PDD. To address this… CONTINUE READING
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