Experimental immunization against Lyme borreliosis with recombinant Osp proteins: An overview

@article{ScDDrAriadnaSadzieneM1996ExperimentalIA,
  title={Experimental immunization against Lyme borreliosis with recombinant Osp proteins: An overview},
  author={D. Sc.D.Dr.AriadnaSadzieneM. and D. Dr.A.G.BarbourM.},
  journal={Infection},
  year={1996},
  volume={24},
  pages={195-202}
}
Interest in human and veterinary vaccines against Lyme borreliosis is growing. Both whole cell immunization and subunit vaccines can protect against infection withBorrelia burgdorferi. For development of a human vaccine the focus has been on a subunit vaccine. The most promising candidate is OspA, a major outer membrane lipoprotein ofB. burgdorferi sensu lato. Of Osp proteins A through D, OspA shows the least variability between strains in its sequence and in the level of its expression… CONTINUE READING

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