Experimental hematogenous candidiasis caused by Candida krusei and Candida albicans: species differences in pathogenicity.

@article{Anaissie1993ExperimentalHC,
  title={Experimental hematogenous candidiasis caused by Candida krusei and Candida albicans: species differences in pathogenicity.},
  author={Elias J. Anaissie and Ray Y. Hachem and C K-Tin-U and L. Clifton Stephens and Gerald Paul Bodey},
  journal={Infection and immunity},
  year={1993},
  volume={61 4},
  pages={1268-71}
}
Hematogenous infections caused by Candida krusei have been noted with increasing frequency, particularly in cancer patients receiving prophylaxis with antifungal triazoles. Progress in understanding the pathogenesis of this emerging infection has been limited by the lack of an animal model. We developed a CF1 mouse intravenous inoculation model of candidiasis to evaluate the pathogenicity of C. krusei in normal and immunosuppressed mice and to compare it with that of Candida albicans. Several… CONTINUE READING