Experimental hantavirus infection in nonhuman primates

  title={Experimental hantavirus infection in nonhuman primates},
  author={Richard Yanagihara and H. L. Amyx and Peter Lee and David Asher and Clarence J. Gibbs and D. Carleton Gajdusek},
  journal={Archives of Virology},
Mild, transient proteinuria and azotemia were produced in three cynomolgus monkeys (Macaca fascicularis) and a chimpanzee (Pan troglodytes) following intravenous inoculation with Prospect Hill virus, a hantavirus isolated from meadow voles in the United States. This is the first demonstration of an acute nephropathy in nonhuman primates with the viruses causing hemorrhagic fever with renal syndrome. 

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Prospect Hill virus: serological evidence for infection in mammalogists

R Yanagihara, DC Gajdusek, CJ JrGibbs, R Traub
N Engl J Med • 1984
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