Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus.

@article{Weber2000ExperimentalGA,
  title={Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus.},
  author={Arthur J. Weber and H Chen and William C Hubbard and Paul L. Kaufman},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 6},
  pages={1370-9}
}
PURPOSE To examine the effects that elevated intraocular pressure (IOP), a glaucoma risk factor, has on the size, density, and number of neurons in the primate lateral geniculate nucleus (LGN). METHODS The monkey model of experimental glaucoma was combined with standard histologic staining and analysis techniques. Fourteen animals were examined. RESULTS Mean IOPs higher than 40 mm Hg for 2.5, 4, 8, and 24 weeks resulted in reductions of 10% to 58% in the cross-sectional areas of LGN neurons… CONTINUE READING

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