Experimental free-energy measurements of kinetic molecular states using fluctuation theorems

  title={Experimental free-energy measurements of kinetic molecular states using fluctuation theorems},
  author={Anna Alemany and Alessandro Mossa and Ivan Junier and Felix Ritort},
  journal={Nature Physics},
Short-lived kinetic states between equilibria are difficult to access experimentally, despite being crucial in many dynamical processes. Single-molecule experiments demonstrate that an extended fluctuation relation allows extraction of the free energies of these metastable states under non-equilibrium conditions. 

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  • G. HummerA. Szabó
  • Physics
    Proceedings of the National Academy of Sciences of the United States of America
  • 2001
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