Experimental evidence for blood pressure-independent vascular effects of high sodium diet.

  • Geza Simon
  • Published 2003 in American journal of hypertension


The two physiologic mechanisms that may be responsible for the adverse cardiovascular effects of long-term high sodium diet without increasing blood pressure (BP) are increased blood flow and increased extracellular sodium concentration. The first dilates arteries, and the second may impact on vascular reactivity and growth. The experimental evidence for… (More)


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