Experimental diabetic neuropathy. Inhibition of protein mono-ADP-ribosylation prevents reduction of substance P axonal transport.

@article{Donadoni1995ExperimentalDN,
  title={Experimental diabetic neuropathy. Inhibition of protein mono-ADP-ribosylation prevents reduction of substance P axonal transport.},
  author={M L Donadoni and R Gavezzotti and Fabio Borella and Anna Maria Di Giulio and Alfredo Gorio},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1995},
  volume={274 1},
  pages={570-6}
}
The extranuclear endogenous mono-ADP-ribosylation of proteins in cellular fractions from retinas of control and diabetic rats was studied. At least six proteins were ADP-ribosylated in the crude extract, membrane and cytosolic fractions from control preparations, whereas in diabetic rats the number of labeled proteins and the extent of labeling were highly… CONTINUE READING