Experimental diabetes induced by alloxan and streptozotocin: The current state of the art.

@article{Radenkovi2016ExperimentalDI,
  title={Experimental diabetes induced by alloxan and streptozotocin: The current state of the art.},
  author={Miroslav Radenkovi{\'c} and Marko Stojanovi{\'c} and Milica Prostran},
  journal={Journal of pharmacological and toxicological methods},
  year={2016},
  volume={78},
  pages={
          13-31
        }
}
Diabetes mellitus is a chronic metabolic disorder with a high prevalence worldwide. Animal models of diabetes represent an important tool in diabetes investigation that helps us to avoid unnecessary and ethically challenging studies in human subjects, as well as to obtain a comprehensive scientific viewpoint of this disease. Although there are several methods through which diabetes can be induced, chemical methods of alloxan- and streptozotocin-induced diabetes represent the most important and… CONTINUE READING

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